Insomnia’s Effect on Middle Age Mortality

 

A new study out of Norway suggests a possible link between insomnia and mortality, but findings are mixed and well-controlled studies are lacking, according to an analysis in BMC Public Health. The aim of the study titled “Midlife insomnia and subsequent mortality: the Hordaland health study” was to examine the effect of insomnia in middle age on all-cause mortality.

 

Using a cohort design with 13-15 years follow-up, mortality registry data were linked to health information obtained during 1997-99, as part of the community-based Hordaland Health Study (HUSK), in Western Norway. More than participants aged 40–45 provided baseline information on self- reported insomnia using the Karolinska Sleep Questionnaire Scale.

 Insomnia’s Effect on Middle Age Mortality  Insomnia’s Effect on Middle Age Mortality  Insomnia’s Effect on Middle Age Mortality  Insomnia’s Effect on Middle Age Mortality  Insomnia’s Effect on Middle Age Mortality  Insomnia’s Effect on Middle Age Mortality

BMC Public Health reports that “Insomnia was reported by 5.6% (349/6236) at baseline and a significant predictor of all-cause-mortality (hazard ratio [HR] = 2.74 [95% CI:1.75-4.30]). Adjusting for all confounders did not attenuate the effect (HR = 3.34 [95% CI:1.67-6.69]). Stratifying by gender, the effect was especially strong in men (HR = 4.72 [95% CI:2.48-9.03]); but also significant in women (adjusted HR = 1.96 [95% CI:1.04-3.67]). The mortality risk among participants with both insomnia and short sleep duration (<6.5 hours) was particularly high, whereas insomnia in combination with normal/greater sleep duration was not associated with mortality.”

 

Researchers concluded that insomnia was associated with “a three-fold risk of mortality over 13-15 years follow-up. The risk appeared even higher in males or when insomnia was combined with short sleep duration, although such unadjusted subgroup analyses should be interpreted with caution.”

 

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