Cardiovascular Co-morbidity Link Explores Link Between Different OSA Types


Taiwanese researchers performed a retrospective cohort study aimed to determine if there are differences in cardiovascular co-morbidities, blood pressure (BP) and CPAP use between patients with positional-dependent and nonpositional-dependent obstructive sleep apnea (OSA).


According to the article titled “Comparison of cardiovascular co-morbidities and CPAP use in patients with positional and non-positional mild obstructive sleep apnea“, the study found that positional mild OSA had less cardiovascular co-morbidities compared with subjects with positional severe OSA. Independent of posture, CPAP acceptance in patients with mild OSA was low, but CPAP compliance was similar in CPAP acceptors regardless of posture dependency of OSA. Since there are increasing evidences of greater cardiovascular risk for untreated mild OSA, improving CPAP acceptance among mild OSA patients may be clinically important regardless of posture dependency.


Researchers screened patients between 2007 and 2011 from the Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Tzuchi Hospital. A total of 371 patients with OSA were included for analysis.


Demographic and anthropometric variables showed non-positional severe OSA had poor sleep quality and higher morning blood pressures. Positional mild OSA had the lowest cardiovascular co-morbidities. Overall CPAP acceptance was 45.6%. Mild OSA patients had the lowest CPAP acceptance rate (10%), followed by moderate group (37.37%) and severe group (61.88%, P < 0.001). However, the significant difference in CPAP acceptance across OSA severity disappeared when the data was stratified by positional dependency.


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